Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors

• Sedat Ünal,
• Gamze Varan,
• Juan M. Benito,
• Yeşim Aktaş and
• Erem Bilensoy

Beilstein J. Org. Chem. 2023, 19, 139–157, doi:10.3762/bjoc.19.14

• positive change in 6-O-capro-β-CD nanoparticles. It is known that the same nanoparticles may have different effects on cancer cells of different species. In addition to the surface charges, particle size and distribution also play a very important role in the cellular interactions of nanoparticles. For

Stereo- and regioselective hydroboration of 1-exo-methylene pyranoses: discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors

• Alexander Dahlqvist,
• Axel Furevi,
• Niklas Warlin,
• Hakon Leffler and
• Ulf J. Nilsson

Beilstein J. Org. Chem. 2019, 15, 1046–1060, doi:10.3762/bjoc.15.102

• /bjoc.15.102 Abstract Galectins are carbohydrate recognition proteins that bind carbohydrates containing galactose and are involved in cell signaling and cellular interactions, involving them in several diseases. We present the synthesis of (aryltriazolyl)methyl galactopyranoside galectin inhibitors

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

• Loïc Leclercq

Beilstein J. Org. Chem. 2016, 12, 2644–2662, doi:10.3762/bjoc.12.261

• reviewed as well as their interactions with isolated biomolecules leading to the formation of inclusion or exclusion complexes. Finally, some potential medical applications are highlighted throughout several examples. Keywords: cellular interactions; cyclodextrins; endogenous substances; extraction

• . For sake of clarity, only some typical applications of CD/cellular interactions are reported. i) Cell membrane cholesterol efflux As previously mentioned, CDs are able to interact and to complex cholesterol and others lipids [114]. A great number of publications deals with this topic and with the

Multivalency as a chemical organization and action principle

• Rainer Haag

Beilstein J. Org. Chem. 2015, 11, 848–849, doi:10.3762/bjoc.11.94

• understanding of multivalent interactions this Thematic Series in the Beilstein Journal of Organic Chemistry puts its focus to unravel new cellular interactions that are highly relevant [2] and systematically combines theoretical exploration of defined multivalent supramolecular interactions [3] as well as new

Molecular architecture with carbohydrate functionalized β-peptides adopting 3₁₄-helical conformation

• Nitin J. Pawar,
• Navdeep S. Sidhu,
• George M. Sheldrick,
• Dilip D. Dhavale and
• Ulf Diederichsen

Beilstein J. Org. Chem. 2014, 10, 948–955, doi:10.3762/bjoc.10.93

• , India Institute for Inorganic Chemistry, Georg-August University Göttingen, Tammannstraße 4, D-37077 Göttingen, Germany 10.3762/bjoc.10.93 Abstract Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and